[Uncommon case of paraganglioma syndrome in combination with malignant paraganglioma]
[Uncommon case of paraganglioma syndrome in combination with malignant paraganglioma]
BACKGROUND: Combination of paraganglioma syndrome and malignant paraganglioma is an uncommon disease worldwide. PATIENT: We report the case of a 69-year old man with a jugular-tympanal paraganglioma, who underwent surgery. Histopathological examination revealed a malignant paraganglioma. An other contralateral carotid-body and a tumor in the thyroid gland had been discovered during staging. The molecular results confirmed the existence of a paraganglioma syndrome. DISCUSSION: A malignant paraganglioma based on a hereditary paraganglioma syndrome is a rare described case in literature. On the background of the literature we discuss the pathology, pathogenesis, diagnostic and therapy of this disease.
Schmahl K, Atamna N, Schönijahn T, Lülsdorf P, Göller T, Jacob R.
Abt. XIII, Pathologie, Bundeswehrzentralkrankenhaus Koblenz.